Vol. 9, Issue 1, Part A (2026)

Background: Systemic hematological abnormalities reflecting inflammatory activity and renal involvement are often linked to severe renal inflammation. It's unknown how much biological sex affects these changes. 
Aim: To compare results between male and female patients and assess hematological parameters in individuals with severe renal inflammation. 
Methods: 140 individuals with severe renal inflammation 70 men and 70 women were included in this cross-sectional study. Using standard laboratory techniques, hematological parameters such as WBC, RBC, hemoglobin, hematocrit, and platelet count were measured. Appropriate statistical tests were used to compare groups, and p<0.05 was deemed statistically significant. 
Results: Neither age nor any of the assessed hematological parameters showed statistically significant variations between male and female patients (p>0.05). Both groups showed similar hematological findings. In conclusion, hematological changes in severe renal inflammation seem to be independent of biological sex, indicating that changes in blood profiles are mostly determined by inflammatory mechanisms connected to the disease.