Vol. 8, Issue 4, Part A (2025)

A 26 year female presented to FNAC clinic with a lump right breast. It was firm, measuring 3x3 cm in central quadrant, FNAC yielded moderately cellular smear, showing presence of antler horn clusters, monolayered sheets and blunt tipped clusters of monomorphic ductal epithelial cells with interspersed myoepithelial cells and bare bipolar nuclei. Scant stromal fragment were seen. Cytological diagnosis of fibroadenoma was given. Subsequent USG, both breasts revealed normal fibro-glandular tissues with predominantly fatty tissues interspersed within, with no definite abnormality. The lesion was excised and we received a specimen size measuring 7x4x3cm, showing circumscribed non-encapsulated lesion. On cut surface, fatty areas admixed with grey white firm areas were seen. Sections showed disorganised TDLU with interspersed adipose tissue and scant area of dense hyalinized stroma. Few ducts were cystically dilated with focal apocrine metaplasia. Lesion was diagnosed as Hamartoma breast. A case is being discussed for overlapping cytological feature with fibroadenoma.