Vol. 8, Issue 1, Part B (2025)

Introduction: COVID-19, caused by SARS-CoV-2, presents with symptoms ranging from mild flu-like symptoms to severe ARDS and organ failure.
Purpose/ Objectives: The objective of this study is to classify COVID-19 cases into mild, moderate, and severe categories, while also evaluating the role of haematological, biochemical, inflammatory, and coagulation parameters in the stratification of disease severity.
Material and Methodology: The descriptive study was used to analyse 500 RT-PCR-positive COVID-19 cases. Analysis of variance was used for clinicopathological correlations. The chi-square test was used to find the association between categorical variables.
Results: In the study, out of 500 total cases, 302 patients (60%) were male, while 198 patients (40%) were female. Statistically significant (p<0.05) and clinically correlated results were found for TC, DC, N:L ratio, D-dimer, serum ferritin, CRP, IL-6, and serum LDH. HB and PT (INR) were significant (p<0.05) but showed no correlation with severity. Platelet count, APTT, and serum creatinine were not statistically significant (p>0.05).
Conclusions: The sociodemographic data, clinical monitoring, and regular lab tests provide a comprehensive approach to understanding and managing COVID-19 disease severity.