Vol. 8, Issue 1, Part A (2025)
Histopathological analysis of skin adnexal tumors at tertiary care hospital
Mardiya Jaydipkumar Bhikhubhai, Sanjay Dhotre, Hitendra Barot, Kajal Parikh, Nikita Chandravadiya, Shreyas Patel and Hansa Goswami
Background: Skin adnexal tumors encompass very broad variety of rare dermatopathologic entities. Adnexal Tumors are a group of skin tumors which are mostly benign in nature. Skin adnexal tumors principally arise from undifferentiated pluripotent stem cells present in the epidermis or appendageal structures that finally differentiate to specific tumors. They are classified into tumors with differentiation towards eccrine or apocrine sweat glands, hair follicle and sebaceous glands.
Materials and Methods: The present study includes cases from January 2015 to June 2024 over period of 9.5 years. Total 72 cases of Skin adnexal tumors were included in this study. Histopathological examination was done on Haematoxylin and eosin sections of paraffin embedded & formalin fixed tissue.
Results: Benign skin adnexal tumors constituted majority of tumors with 71 out of 72 (98.6%) while only one case of malignant skin adnexal tumor was encountered. The sweat gland tumors present for largest numbers of cases with 47/72 (65.3%) followed by hair follicle tumors 22/72 (30.6%) and sebaceous gland 3/72 (4.1%).
Conclusion: Skin adnexal tumors are rare neoplasms with benign being far more common than malignant. Skin adnexal tumors often misdiagnosed clinically, so histopathological examination is the gold standard for establishing accurate diagnosis and better patient management.
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