Vol. 7, Issue 3, Part E (2024)

Background: Gliomas account for the great majority of primary tumors that arise within the brain parenchyma. The term "glioma" refers to tumors that have histologic features similar to normal glial cells (i.e., astrocytes, oligodendrocytes and ependymal cells).

Aims & objectives: The present study aims towards histopathological study of various supratentorial gliomas. To evaluate the frequency, age, sex, site wise distribution and clinical presentation of the various gliomas.

Materials and Methods: The present histopathological study was undertaken in the department of pathology, B.J. Medical College, Civil Hospital Ahmedabad on surgical specimens received from department of neurosurgery Civil Hospital Ahmedabad from July 2022 to June 2024. Histopathological examination was correlated with detailed clinical findings and other relevant investigations.

Inclusion Criteria: All specimen having Supratentorial glioma lesions with adequate histology material received at Histopathology Department.

Exclusion Criteria: The superficial biopsy, biopsy with artefacts and inadequate material/history was excluded from the study.

Results: Out of 100 cases, maximum cases of Supratentorial gliomas were found in middle aged individuals, the most common age group affected was 41-50 years followed by 31-40 years of age group. Headache followed by convulsions were most common presenting symptoms. In present study most of the lesions were localized to frontal lobe (35%) followed by temporal lobe (32%), parietal lobe (23%) and 10% included other sites such as occipital cortex or insular lobe.

Conclusion: The present study highlights the histopathological study of various gliomas in both adult and pediatric age groups. Although with the advent of modern imaging techniques, a provisional diagnosis could be given, but histopathological examination with futher utilization of IHC remains the gold standard in diagnosis. The surgical pathologist plays an important role in accurate diagnosis of various gliomas which is of immense help for patient prognosis and treatment.