Vol. 7, Issue 3, Part D (2024)
Histopathological study of nephrectomy specimens in tertiary care hospital
Author(s):
Saloni Parikh, Hansa Goswami and Urvi Parikh
Abstract:
Background and Aim: Function of human kidneys is to produce about 1 L of a highly concentrated fluid called urine from more than 1700 L of blood per day. Kidney diseases can be divided into those that affect the four basic morphologic components: glomeruli, tubules, interstitium, and blood vessels. The study here is done to observe various histopathological findings in nephrectomy specimens received in our tertiary care hospital which caters both rural and urban population. Study also focuses on age and sex distribution, neoplastic and non-neoplastic distribution along with the histopathological features.
Material and Methods: The study was carried out for a period of 1year from March 2023 to February 2024 which included all the nephrectomy specimen received in the department of pathology, B.J Medical College, Ahmedabad, Gujarat. A total of 50 nephrectomy specimens were received in the given study period. Patient particulars including age, sex, clinical diagnosis along with gross morphology and microscopic details were noted form the data available with our department.
Result: In the present study male to female ratio is of 2.1:1. Maximum patients with nephrectomy were in the age group of 45-60 yrs. The data according to age incidence, sex incidence and nature of the lesion was prepared and analyzed. 34 (68%) cases were of non-neoplastic lesions while 16 (32%) cases were of neoplastic lesions. Among neoplastic lesions 6 (37.5%) cases are benign and 10(62.5%) cases are malignant. Renal cell carcinoma is most common among malignant lesions.
Conclusion: Chronic Pyelonephritis is most common non-neoplastic cause of nephrectomy. Non-neoplastic lesions were most common cause for nephrectomies. Clear cell renal cell carcinoma is most common among malignant tumors. Increase in availability of early diagnosis and appropriate better targeted treatment facilities for renal disorders can cause decrease in need of surgical treatment for non-neoplastic lesions of kidney.
Pages: 235-240 | 99 Views 40 Downloads
How to cite this article:
Saloni Parikh, Hansa Goswami and Urvi Parikh. Histopathological study of nephrectomy specimens in tertiary care hospital. Int. J. Clin. Diagn. Pathol. 2024;7(3):235-240. DOI: 10.33545/pathol.2024.v7.i3d.606
