Vol. 7, Issue 3, Part A (2024)

Introduction: Urinary bladder encompasses a wide variety of lesions, both neoplastic and nonneoplastic responsible for significant morbidity and mortality throughout the world. All bladder lesions require biopsy because of their lack of distinctive features. Urinary bladder cancer is the 9th most common cancer worldwide accounting for 6% and 2% of the cancer incidence in men and women, respectively.90% of the bladder tumors are of urothelial origin. Cystoscopic examination has a limited role in staging process for which transurethral resection (TURBT) of visible tumor down to the base is required which can accurately assess depth of tumor invasion. This study is aimed to study the different spectrum of urinary bladder lesions in tertiary level hospital.

Aim: To analyse the histopathological spectrum of bladder specimens with neoplastic and nonneoplastic lesions, and categorising them according to recent 2022 World Health Organisation (WHO) classification.

Material and method: A total of 86 cases of urinary bladder biopsy of patient admitted in civil hospital were studied over the period from January-2022 to June-2024 in department of pathology.

The cystoscopic biopsies and TURBT biopsies were fixed in 10% formalin solution. The specimens were subjected to standard paraffin embedding and hematoxylin and eosin staining.

Results: Maximum number of patients are in age group 61-70 years. Males are more frequently affected as compared to female.

Conclusion: A variety of urinary bladder lesions are commonly encountered in our day to day practice. In our study, the bladder lesions were commonly seen in age group of 61-70 years of life with overall a male preponderance. Also, this study, documented a high frequency of invasive than non invasive type of urothelial neoplasm. Invasive urothelial carcinoma, high grade constituted the commonest of urothelial tumors.