Spectrum of histopathological lesions of nasal cavity, paranasal sinus and nasophrynx at tertiary care centre
Dr. Mushkan A Sorathya, Dr. Arpita Makwana and Dr. Nandini J Desai
Introduction: The lesions of nasal cavity and paranasal sinuses provides problems in their diagnosis, prognosis and management because of limited anatomical space and certain unusual clinicopathological features.
Materials and Methods: The present study was carried out on 50 patients. Types of samples include biopsies or total specimens from nose, para nasal sinuses and nasophrynx received in histopathology section of the pathology department. The cases were diagnosed based routine H& E stained section slide via light microscopy.
Aims and Objectives: To study the incidence of various non neoplastic and neoplastic lesion with, age and sex distribution along with their clinical presentation and various Histopathological patterns.
Results: A total of 50 specimens from representative areas were studied. Age distribution varied from 0 to >70 years with male preponderance. Non - Neoplastic lesions were common comprising of 32 cases (54%) while neoplastic lesions were 23 (46%). Among non neoplastic lesions inflammatory polyp (12 cases) was common followed by allergic polyp (10 cases). In neoplastic lesions, squamous cell carcinoma (06 cases) predominated.
Conclusion: It shows wide range of non neoplastic lesion in the complex region of nose, paranasal sinus and nasophrynx. Non neoplastic lesions were far common as compared with neoplastic lesion. Radiological studies and other investigation can help provide a differential diagnosis, but the final diagnosis can only be given on Histopathological examination. Definite diagnosis is essential for further management and to determine the prognosis of the patient. Therefore histopathology plays an integral role and remains gold standard for establishing the diagnosis of sinonasal tract pathology.
