Vol. 6, Issue 3, Part A (2023)
Rare variant of renal cell carcinoma: A case report from rural tertiary care centre
Author(s):
Dr. Keerthyraj N, Dr. V Sriram, Dr. Revathi G, Dr. V Vigneswaramoorthi, Dr. Erli Amel Ivan and Dr. Ramya G
Abstract:
Introduction: Renal Cell Carcinoma (RCC) is the most common type of kidney cancer, accounting for 3% of all malignancies and 85% of all malignant kidney tumors. The histological classification is of utmost importance, considering the significant prognostic and therapeutic implications of these histological subtypes. Here we report rare variant of RCC which include Oncocytic variant of papillary renal cell carcinoma (OPRCC).
Case report: A middle age male presented with pain in left flank and decreased urine output. CECT Abdomen revealed a well defined solid cystic mass lesion arising from inferior polar cortex of the left kidney measuring 10.9 x 9.4 x 9.8 cm. Left radical nephrectomy was performed and the specimen was sent for histopathological examination and show features of oncocytic variant of papillary renal cell carcinoma.
Conclusion: The importance of this case report is to identify the rare variants of the histological subtypes of RCC as it confers high propensity of metastasis and hence less chance of survival. OPRCC is regarded as an independent subtype of PRCC not only for its distinct pathological features but also for its indolent clinical behaviour and the tumor presents with same immunophenotypic as of type 2 but same genetic features and prognosis as of type 1 PRCC.
Pages: 07-08 | 503 Views 158 Downloads
How to cite this article:
Dr. Keerthyraj N, Dr. V Sriram, Dr. Revathi G, Dr. V Vigneswaramoorthi, Dr. Erli Amel Ivan and Dr. Ramya G. Rare variant of renal cell carcinoma: A case report from rural tertiary care centre. Int. J. Clin. Diagn. Pathol. 2023;6(3):07-08. DOI: 10.33545/pathol.2023.v6.i3a.527
