International Journal of Clinical and Diagnostic Pathology

International Journal of Clinical and Diagnostic Pathology

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Vol. 5 Issue 4 Part B

2022, Vol. 5 Issue 4, Part BPages: 90-94

Histopathological study of benign proliferative breast lesions in peritumoral area of carcinoma breast - experience in a tertiary care centre

Dr. Bejoy Ravindran N, Dr. Jayasree PV, Dr SS Mega Samly and Dr. Rajan G
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ABSTRACT
Background: Lesions of breast has gained more importance worldwide due to increase in mortality and morbidity associated with breast cancer. In India increase in incidence is due to life style changes and use of hormones. Presence of different proliferative lesions adjacent to malignancy in the same breast proves that carcinogenesis of breast is a multistep process. Women with proliferative breast lesions are more prone to develop carcinoma. Knowledge in carcinogenesis of breast will define the high risk group that improves the screening for carcinoma and management
Aim: The aim is to study the histopathological types of carcinoma breast and benign proliferative breast lesions in peritumoral area.
Materials and Method: This study was a cross-sectional study conducted for a period of 2 years. A total of 85 cases that satisfy the inclusion criteria were included in the present study. Samples were collected in 10% formalin. All the tissue specimens were processed and paraffin embedded. The sections were stained with Hematoxylin and Eosin. Histopathology findings were noted. Results thus obtained was analyzed using SPSS 20.0 version. Statistical analysis was done using Chi square test.
Results: Common age group affected was between 51 to 60 years seen in 30(35.3%) cases. Lesions were predominantly seen in right breast 39 (45.9%). Invasive carcinoma breast No Special Type was the most common malignant lesion (85.9%). Non proliferative breast lesion was common in peritumoral area 46(54.1%). Statistical significance was observed between histopathological diagnosis, tumour size, lymph node status and peritumoral benign proliferative breast lesions.
Conclusion: Proliferative epithelial lesions are at increased risk of subsequent breast cancer. Non proliferative breast diseases are the most common peritumoral lesion in the present study. Even though the risk of transformation to malignancy is less, careful follow-up with clinical breast examination and annual mammographic screening every 6 to 12 months can identify the changes and further it helps to reduce the occurrence of invasive breast cancer.


International Journal of Clinical and Diagnostic Pathology
How to cite this article:
Dr. Bejoy Ravindran N, Dr. Jayasree PV, Dr SS Mega Samly, Dr. Rajan G. Histopathological study of benign proliferative breast lesions in peritumoral area of carcinoma breast - experience in a tertiary care centre. Int J Clin Diagn Pathol 2022;5(4):90-94. DOI: 10.33545/pathol.2022.v5.i4b.497
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