International Journal of Clinical and Diagnostic Pathology

International Journal of Clinical and Diagnostic Pathology

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International Journal of Clinical and Diagnostic Pathology

2022, Vol. 5 Issue 4, Part APages: 32-35

Incidence & prevalence of leukemia with sub-typing in tertiary care centre: A retrospective & prospective study

Dr. Akshar M Chauhan, Dr. Neeru D Dave and Dr. Minaxi Patel
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ABSTRACT
Introduction: Leukemia is a heterogeneous group of haematological malignancies that comprises several diverse and biologically distinct subgroups. The exact cause of leukemia is not yet clear. However, several factors, mainly hereditary inheritance, genetic mutations, epigenetic lesion, ionic radiation, chemical and other occupational exposures, therapeutic drugs, smoking, and some viral agents, have been implicated in developing leukemia. It is one of the fatal diseases and their morbidity and mortality rates increase day by day all over the world.
Material and Method: 52 patients of leukemia were evaluated during May 2020 to June 2022 retrospectively & prospectively having chief complains of fatigue, weakness, infections, bleeding tendencies & bone pain out of total 81552 presenting to the OPD.
Result: It was found that leukemia was equally prevalent in male and female patients, ratio being 1: 1 & most of the patients were over the age of 51 years. It was also observed that chronic leukemia was more prevalent than acute leukemia. Amongst types of leukemia, Acute myelogenous Leukemia (AML) was more prevalent (29 %) than Acute lymphocytic Leukemia (ALL) (10 %), similarly Chronic lymphocytic leukemia (CLL) was more prevalent (34%) than chronic myeloid leukemia (CML) (27%).
Conclusion: Chronic leukemia was more prevalent than acute leukemia in this part of the country and its risk factors & pathogenesis needs to be addressed so that modifiable risk factors can be reduced to a minimum.
How to cite this article:
Dr. Akshar M Chauhan, Dr. Neeru D Dave, Dr. Minaxi Patel. Incidence & prevalence of leukemia with sub-typing in tertiary care centre: A retrospective & prospective study. Int J Clin Diagn Pathol 2022;5(4):32-35. DOI: 10.33545/pathol.2022.v5.i4a.490
International Journal of Clinical and Diagnostic Pathology
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