International Journal of Clinical and Diagnostic Pathology

International Journal of Clinical and Diagnostic Pathology

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International Journal of Clinical and Diagnostic Pathology

2022, Vol. 5 Issue 3, Part APages: 12-15

Comparative study of significance of serum human epididymis protein 4 (HE4) and carbohydrate antigen 125 (CA125) as an early tumour marker in female patients with ovarian cancer

Geeta Bilonia, Dr. Rati Mathur and Dr. Suresh Singh
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ABSTRACT
Aim: To determine the usefulness of serum human epididymis protein4 (HE4) along with Carbohydrate Antigen 125 (CA125) as an early tumour marker in female patients with ovarian cancer.
Method: The ovarian cancer patients were recruited from OPD/IPD of Surgery and Oncology department of SMS Hospital, and evaluated serum HE4 and CA125. Total 262 subjects were included in this study.131 ovarian cancer Patients were divided according to different stages and 131 control subjects also included.
Results: Serum HE4 and CA125 level raised significantly in ovarian cancer patients. Further increases with the advanced stage of the ovarian cancer.
Conclusion: Both HE4 and CA125 can be useful diagnostic tumour marker in ovarian cancer.
How to cite this article:
Geeta Bilonia, Dr. Rati Mathur, Dr. Suresh Singh. Comparative study of significance of serum human epididymis protein 4 (HE4) and carbohydrate antigen 125 (CA125) as an early tumour marker in female patients with ovarian cancer. Int J Clin Diagn Pathol 2022;5(3):12-15. DOI: 10.33545/pathol.2022.v5.i3a.472
International Journal of Clinical and Diagnostic Pathology