International Journal of Clinical and Diagnostic Pathology

Malignant transformation of mature cystic teratoma is a rare phenomenon and often a diagnostic challenge. We present a case of a 42-year-old female presenting with abdominal distension. CECT abdomen revealed a solid cystic tubo-ovarian mass in pelvis which was then resected. On histopathological examination of the resected specimen a diagnosis of Malignant transformation of MCT with the possibility of malignant component to be Squamous cell carcinoma or Clear cell carcinoma was given. On Immunohistochemical evaluation the malignant component was confirmed to be Squamous cell carcinoma.