Vol. 5, Issue 4, Part B (2022)

Background: Nephrectomy is a standard surgical procedure and all specimens were studied for the evaluation of Non- Neoplastic and Neoplastic lesions of kidney and compare it with other studies over a period of 1 year in Pathology department at Guru Gobind Government Hospital, Shri M. P. Shah Government Medical College, Jamnagar.

Materials and Methods: The study was carried out on 25 nephrectomy specimens over a period of 1 year, and histopathological diagnosis given on the basis of light microscopic findings.

1.To find out the different histopathological findings in received nephrectomy specimen.

2.To analyze gender and age wise frequency of the neoplastic and non- neoplastic lesions of the kidney.

3.To study different lesions and to evaluate the rare conditions.

Results: Among 25 nephrectomy specimens age range was 4-90 years and highest incidence was observed 41-50 years of age group with 36% (9 cases) while Lowest percentage of patients belonged to <10 years age group with 4% (1 case), female patients were 9 cases (36%), male patients were 16 cases (64%). Youngest age was 4 year (Clear cell Sarcoma) and oldest age was 90 years (Papillary Renal Cell Carcinoma), non-neoplastic lesions were common comprising 68% (17 cases) in which Chronic Pyelonephritis was the most common accounting to 40% (10 cases) and neoplastic lesions were 32% (8 cases) in which Renal Cell Carcinoma- Clear Cell Type were common accounting to 20% (05 cases).

Conclusion: Non neoplastic lesions were more common than neoplastic lesion among which chronic pyelonephritis was the most common and renal cell carcinoma -Clear cell type was the common among all the neoplastic tumors. Peak age of incidence was 5th decade with chief complain of flank pain.