International Journal of Clinical and Diagnostic Pathology

International Journal of Clinical and Diagnostic Pathology

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International Journal of Clinical and Diagnostic Pathology

2021, Vol. 4 Issue 4, Part BPages: 113-119

Fixation and different types of fixatives: Their role and functions: A review

Ashaq Hussain Bhat and Samiea Hussein
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ABSTRACT
Fixation is a complete and complex physiochemical process wherein cells and tissues are chemically fixed for further analyses. Fixatives are used for Solidification, Hardening, Optical differentiation, prevention of autolysis and tissue putrefaction. Various Types of fixatives (Simple, Compound, Microanatomical, Histochemical and Cytological) are used in Histology and Histopathology which includes Mercuric Chloride, Osmic Acid, formaldehyde, glutaraldehyde, osmium tetroxide, glyoxal, picric acid, Zenker’s fluid and so on. Due to limited availability of the material related to the topic a need was felt to write a review article so as to make the Researchers, Students. pathologists and laboratory technicians familiar with the basic Concept of fixation and fixatives.
How to cite this article:
Ashaq Hussain Bhat and Samiea Hussein. Fixation and different types of fixatives: Their role and functions: A review. International Journal of Clinical and Diagnostic Pathology. 2021; 4(4): 113-119. DOI: 10.33545/pathol.2021.v4.i4b.433
International Journal of Clinical and Diagnostic Pathology