Study of serum prostate specific antigen levels in patients with prostate lesions

In order to see a relationship between histopathology and PSA levels, group of 100 men were studied which included obtaining there Histopathological diagnosis and serum PSA levels before surgical intervention. We found that most common pathology encountered in prostate specimen is BPH. Most of disease of prostate occur in the age group of 61-70 years. With increasing PSA levels the possibility of malignancy increases. But Poorly differentiated tumor may not correlate with PSA level because the tumor cells may not produce PSA as they have lost differentiation.