International Journal of Clinical and Diagnostic Pathology

International Journal of Clinical and Diagnostic Pathology

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International Journal of Clinical and Diagnostic Pathology

2021, Vol. 4 Issue 4, Part APages: 11-13

Spectrum of paediatric liver diseases in tertiary health care centre

Dr. Sharma Swapnil, Dr. Kudrimoti JK and Dr. Nakate LA
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ABSTRACT
Introduction: The spectrum of liver diseases is different in children and adults. Development of non-invasive diagnostic methods and advanced hepatic imaging has changed the role of liver biopsy, it is still important in evaluation of paediatric liver disease.
Material and Method: This is an observational, hospital-based study of 32 liver biopsies received during period of 5 years (January 2014-October 2019), comprising cases upto 12 years of age.
Results: In the 32 liver biopsies studied, male to female ratio was 0.68, extrahepatic biliary atresia was commonest histological finding followed by glycogen storage disorder and neonatal hepatitis. Common presentation was Jaundice and hepatomegaly. Clinical and biochemical investigation correlation among biliary atresia and non-biliary atresia group was done.
Conclusion: Liver biopsy assisted by a good clinical examination, radiology and laboratory evaluation can succeed in diagnosis of majority of liver diseases where clinical and laboratory parameters overlap.
How to cite this article:
Dr. Sharma Swapnil, Dr. Kudrimoti JK and Dr. Nakate LA. Spectrum of paediatric liver diseases in tertiary health care centre. International Journal of Clinical and Diagnostic Pathology. 2021; 4(4): 11-13. DOI: 10.33545/pathol.2021.v4.i4a.415
International Journal of Clinical and Diagnostic Pathology