Objective: The coronavirus disease (COVID-19) sparked from Wuhan city of China and rapidly developed into a pandemic. The critically ill patients of COVID-19 exhibit features of hyper inflammation, and the particular blood tests may be rewarding for prognosis. Our aim was to investigate the CBC, which includes total leukocyte, lymphocytes and granulocytes count, Hemoglobin, MCV, MCH, MCHC, RBCs and Platelet count, NLR etc. The current study was conducted to conclude the alteration in blood parameters and their association with the severity and mortality of COVID-19 patients.
Methods: An observational cross-sectional study was conducted retrospectively, a total of 100 COVID-19 positive patients were examined: 50 were mild, 25 were moderate, 10 were severe, and 15 were critically diseased patients. Unfortunately, we recorded 6 deaths among the critical group. The overall mean age observed in our study was 48.94 years, where the mean age for critical individuals was 62.12 ± 14.35 years.
Results: A significant association between the disease severity and elevation in blood parameters were observed. The total WBC's and Neutrophils count were significantly decreased (p value<0.001). The lymphocyte count was increased in critical patients (1.40 × 109 /L) compared to mild patients (1.92 × 109 /L) (p = 0.28).
Conclusion: These blood parameters could be used as a suitable biomarker for the prognosis and severity of COVID-19. Evaluating novel hemograms, NLR can aid clinicians to identify potentially severe cases at early stages, initiate effective management in time, and conduct early triage which may reduce the overall mortality of COVID-19 patients.