Study of platelet indices in diabetes mellitus patient with respect to HbA1c and its correlation with diabetic complications

Dr. Archanaba Gohil; Dr. Sanjay Dhotre; Dr. Bhavesh Faldu; Dr. Hansa Goswami

doi:10.33545/pathol.2021.v4.i3b.391

Study of platelet indices in diabetes mellitus patient with respect to HbA1c and its correlation with diabetic complications

Dr. Archanaba Gohil, Dr. Sanjay Dhotre, Dr. Bhavesh Faldu and Dr. Hansa Goswami

DOI: https://doi.org/10.33545/pathol.2021.v4.i3b.391

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ABSTRACT

Introduction: Diabetes Mellitus (DM) is a pandemic health problem. It is considered as a prothrombotic state with enhanced platelet activity. The increased platelet activity is emphasized to play a role in the development of vascular complications of the metabolic disorder. Mean platelet volume (MPV) is an indicator of average size and activity of platelets. This study was conducted to find correlation of platelet indices with HbA1c in diabetic patients with absence/presence of vascular complications.

Material and Method: Total of 150 patients who were suffering from Type 2 DM and attended Outpatient Department (OPD) in civil hospital Ahmedabad were studied from December 2020 to March 2021. Platelet Indices were measured using automated haematology analyser. The statistical evaluation is done using SPSS version 22. Analysis of variance (ANOVA) is used to compare two variables namely HbA1c <7 and HbA1c ≥7 and diabetics with vascular complications v/s without vascular complications.

Result: MPV is higher in patient with poor glycemic control (HbA1c >7) and in those with vascular complications in compare to patient with HbA1c <7 and those without vascular complications.

Conclusion: The higher values of platelet indices indicates that they serve as better risk indicator of initial vascular complications in diabetes mellitus patients and can be used as a simple and cost-effective tool to assess vascular events.

International Journal of Clinical and Diagnostic Pathology

Vol. 4 Issue 3 Part B

Study of platelet indices in diabetes mellitus patient with respect to HbA1c and its correlation with diabetic complications

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