Comparative study of significance of serum matrix metalloproteinase-13 (MMP-13) and carbohydrate antigen 15.3 (CA15.3) as an early tumor marker in female patients with breast cancer

Sangeeta Yadav; Dr. Rati Mathur; Dr. Suresh Singh

doi:10.33545/pathol.2021.v4.i3b.395

International Journal of Clinical and Diagnostic Pathology

2021, Vol. 4 Issue 3, Part BPages: 99-102

Comparative study of significance of serum matrix metalloproteinase-13 (MMP-13) and carbohydrate antigen 15.3 (CA15.3) as an early tumor marker in female patients with breast cancer

Sangeeta Yadav, Dr. Rati Mathur and Dr. Suresh Singh

DOI: https://doi.org/10.33545/pathol.2021.v4.i3b.395

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ABSTRACT

Aim: To determine the usefulness of serum Matrix metalloproteinase-13 (MMP-13) along with Carbohydrate Antigen 15.3 (CA15.3) as an early tumor marker in female patients with breast cancer.

Method: The breast cancer patients were recruited from OPD/IPD of Surgery and Oncology department of SMS Hospital, and evaluated serum MMP-13 and CA15.3. Total 180 subjects were included in this study.90 breast cancer Patients were divided according to different stages and 90 control subjects also included.

Results: Serum MMP-13 and CA15.3 level raised significantly in breast cancer patients. Further increases with the advanced stage of the breast cancer.

Conclusion: Both MMP-13 and CA15.3 can be useful diagnostic tumor marker in breast cancer.

How to cite this article:

Sangeeta Yadav, Dr. Rati Mathur and Dr. Suresh Singh. Comparative study of significance of serum matrix metalloproteinase-13 (MMP-13) and carbohydrate antigen 15.3 (CA15.3) as an early tumor marker in female patients with breast cancer. International Journal of Clinical and Diagnostic Pathology. 2021; 4(3): 99-102. DOI: 10.33545/pathol.2021.v4.i3b.395