International Journal of Clinical and Diagnostic Pathology

International Journal of Clinical and Diagnostic Pathology

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International Journal of Clinical and Diagnostic Pathology

2021, Vol. 4 Issue 3, Part APages: 32-35

Analysis of cause of death and histopathological stages of diffuse alveolar damage in lung: An autopsy study

Dr. Anandkumar A Chauhan, Dr. Toral Jivani and Dr. Arunima Banerji
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ABSTRACT
Introduction: Diffuse alveolar damage (DAD) is histopathological finding of acute respiratory distress syndrome (ARDS). ARDS is associated with disorders such as poisoning, sepsis, trauma, etc. Aims and objective: Analysis of cause of death and histopathological stages of diffuse alveolar damage in lung autopsy Material and method: Multiple section taken during grossing of lung specimen and processed with subsequent staining by haematoxylin and eosin, stained slide were examined by experienced pathologist under a light microscope. Result: 34 out of 536 individuals who were diagnosed with DAD 9(26.47%) were female and 25 (73.53%) were male. Microscopic finding shows that 27(79.41%) cases were in the exudative phase, and 7 (20.59%) were in the organizing (proliferative) phase. Macrophage desquamation, pulmonary edema and alveolar epithelial cell desquamation were present in majority of patient. Conclusion: Aged individual are frequently affected and particularly in sepsis, intoxication, poisoning, trauma and fire. Forensic autopsies may provide a platform for increasing our knowledge about DAD, acute lung damage and interstitial lung disease.
How to cite this article:
Dr. Anandkumar A Chauhan, Dr. Toral Jivani and Dr. Arunima Banerji. Analysis of cause of death and histopathological stages of diffuse alveolar damage in lung: An autopsy study. International Journal of Clinical and Diagnostic Pathology. 2021; 4(3): 32-35. DOI: 10.33545/pathol.2021.v4.i3a.386
International Journal of Clinical and Diagnostic Pathology