Vol. 4, Issue 3, Part B (2021)
Comparative study of significance of serum matrix metalloproteinase-13 (MMP-13) and carbohydrate antigen 15.3 (CA15.3) as an early tumor marker in female patients with breast cancer
Author(s):
Sangeeta Yadav, Dr. Rati Mathur and Dr. Suresh Singh
Abstract:
Aim: To determine the usefulness of serum Matrix metalloproteinase-13 (MMP-13) along with Carbohydrate Antigen 15.3 (CA15.3) as an early tumor marker in female patients with breast cancer.
Method: The breast cancer patients were recruited from OPD/IPD of Surgery and Oncology department of SMS Hospital, and evaluated serum MMP-13 and CA15.3. Total 180 subjects were included in this study.90 breast cancer Patients were divided according to different stages and 90 control subjects also included.
Results: Serum MMP-13 and CA15.3 level raised significantly in breast cancer patients. Further increases with the advanced stage of the breast cancer.
Conclusion: Both MMP-13 and CA15.3 can be useful diagnostic tumor marker in breast cancer.
Pages: 99-102 | 1112 Views 408 Downloads
How to cite this article:
Sangeeta Yadav, Dr. Rati Mathur and Dr. Suresh Singh. Comparative study of significance of serum matrix metalloproteinase-13 (MMP-13) and carbohydrate antigen 15.3 (CA15.3) as an early tumor marker in female patients with breast cancer. Int. J. Clin. Diagn. Pathol. 2021;4(3):99-102. DOI: 10.33545/pathol.2021.v4.i3b.395
