Leukemia is a hematological disorder which needs timely diagnosis and early treatment because at initially leukemic cell burden is low. So, the chances of achieving complete remission will be highest.
The present study was undertaken for correlation of patient’s signs and symptoms with their laboratory findings like CBC, peripheral smear findings, immunophenotyping to know the lineage specificity and cytogenetics to know molecular abnormality.
Methods and Material: The blood samples of suspected patients were received and examined at Hematology and Surgical pathology sections of Central Diagnostic Laboratory from November 2018 to June 2020. The clinical history was obtained, CBC was performed, peripheral smear and bone marrow samples were received for morphological examination and special investigations like Immunophenotyping, Cytogenetics and fish.
Results: Out of the 110 cases, 17 were ALL, 33 were AML, 16 were CLL, 29 were CML. other 15 cases were distributed in acute leukemia, lymphoma, myelofibrosis and acute undifferentiated leukemia.
Conclusions: Present study revealed that acute leukemia was more prevalent than chronic leukemia. The most common type of leukemia was AML followed by CML, ALL and CLL. ALL was mostly observed in children whereas CML and CLL were mostly observed in adults. AML mostly observed in adults.