International Journal of Clinical and Diagnostic Pathology

Aim and Objectives: The present study is done to analyse the prevalence of various upper gastrointestinal lesions received in our institution and their histopathological findings for early diagnosis which helps in better patient management.

Materials and Methods: A study was conducted in all upper gastrointestinal endoscopic biopsies received in our hospital from June 2016 to May 2017. The patient of all ages and both sexes who underwent endoscopic biopsy was included and analysed on haematoxylin and eosin stained sections.

Results: A total of 259 cases were studied. Patient’s age ranging from 21 to 74 years was taken. Males were more prevalent. Stomach was the commonest site of endoscopic biopsies. The histopathology revealed non-neoplastic lesions 173 (66.80%) and neoplastic lesions 86 (33.20%). Most common non-neoplastic lesion was 51 cases of chronic non specific gastritis. In neoplastic lesions of stomach, adenocarcinoma was the commonest.

Conclusions: Endoscopic procedure along with histo­pathological interpretation still remains as a mainstay of diagnostic modality. So Histopathology is considered as gold standard for the diagnosis of endoscopically detected lesions which helps in early detection of mucosal lesions, both benign and malignant. Histopathology acts as a powerful diagnostic tool in better management and survival of patients.