International Journal of Clinical and Diagnostic Pathology

Granular cell tumours (GCTs) are uncommon tumours of neurogenic origin, thought to originate from Schwann cells. They are most commonly seen in skin, subcutaneous tissues and oral cavity, and are rarely found in gastrointestinal tract (8-10% of cases). Esophageal involvement is seen only in 2% cases. They are slow growing in nature, usually are asymptomatic and detected incidentally during investigation for other gastrointestinal causes. Because of the rarity of GCTs in clinical practice, proper workup and management are essential to avoid the potential morbidity and mortality. Endoscopic submucosal resection is the primary treatment which is done in most cases. Herein, we report a case of 85 year old female who was worked up for dyspepsia and dysphagia and was diagnosed as a case of Granular cell tumour on histopathology.