International Journal of Clinical and Diagnostic Pathology

Tuberculosis caused by Mycobacterium Tuberculosis is very common infectious diseases in India primarily affecting lungs. Various diagnostic modalities are available at present for diagnosis of tuberculosis. CBNAAT (cartridge based nucleic acid amplification test) is a newer modality recommended by World Health Organization. It is very sensitive method and can detect even if few bacilli are present in the sample. Fluorescent microscopy is also very sensitive method and need a fluorescent microscope. As in our study out of 120 patients, five patients were positive only in CBNAAT while four patients were positive only in fluorescent staining. This indicates that fluorescent staining method and CBNAAT should be used together for the early detection of pulmonary tuberculosis.