Meningiomas are most common primary intracranial neoplasm and predominantly benign tumors. Meningioma is characterised by increased number and growth of normal meningothelial cells. There was WHO grading, WHO I- Benign meningioma, WHO II -Atypical meningioma, WHO III- Malignant meningioma.
Aims and objectives: To study the histomorphological variants of meningiomas, the incidence of age, gender & anatomical location of meningioma, and to grade meningiomas according to WHO grading system.
Materials and methods: The study comprised of 50 cases received in department of surgical Pathology, B.J. Medical College, Ahmedabad during period of one year. Case history were studied in detail with respect to presenting symptoms, site, age and sex distribution.
Results: In our study, a total 50 cases of meningiomas were studied, in which meningiomas were most common in the age group between 30-50yrs. In the study of 50 cases, male and female ratio were 1:4. So, meningiomas were more common in female patients. Among all other histological variants of meningiomas, 47 cases from intracranial origin, 3 cases from spinal origin. So intracranial (parietal lobe) meningiomas cases were more common which comprises 15 cases. Majority of cases presented with complains of headache. Most common histological subtype was found to be Meningothelial meningioma which consist of 16 cases. According to the World Health Organization (WHO) grading, WHO grade I consists of 45 cases, WHO grade II consists of 3 cases of meningioma, among them three cases were of atypical meningioma, WHO grade III consists of two cases. Most meningioma were benign in WHO grade I.
Conclusion: Meningiomas are most common intracranial neoplasm comprises about one fourth of all primary tumors of the central nervous system. Meningiomas are predominantly benign tumors. The histological subtype of meningioma and grading determines management and patient’s prognosis. Grade I meningiomas are curable by surgical resection and prognosis depends on complete removal of tumor. Grade II meningiomas show aggressive clinical behaviour with increased rate of recurrence. Grade III meningiomas are capable of malignant clinical behaviour and distant metastasis.