International Journal of Clinical and Diagnostic Pathology

International Journal of Clinical and Diagnostic Pathology

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International Journal of Clinical and Diagnostic Pathology

2020, Vol. 3 Issue 1, Part GPages: 435-442

Non-neoplastic urothelial lesions and mimickers of malignancy: Take Cognizance - Avoid negligence

Dr. Prithal G, Dr. Smitha B, Dr. Muktha R Pai, Dr. Sandhya I and Dr. Purnima S Rao
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ABSTRACT
Background: The differential diagnosis of urothelial neoplasms also includes several histologic mimics, the importance of which cannot be overemphasized since misdiagnosis could have serious clinical and prognostic implications.
Aims: To study the variety of non-neoplastic lesions of the urothelial tract that could potentially be confused with urothelial neoplasms.
Material and Methods: A retrospective and prospective study of five years duration was done at a tertiary care hospital including 55 cases of non-neoplastic urothelial lesions. Results were analysed using SPSS22.
Results: Out of 43.62% of cases clinically suspicious for malignancy, majority (18.18%) were florid Proliferation of von brunn nests. Out of 56.3% cases clinically non-suspicious for malignancy majority were nonspecific cystitis (12.72%). The nonneoplastic lesions were more common in males (83.3%). The mean age was 45.6 yrs.
Conclusions: Diagnostic awareness of salient histomorphologic features of the benign mimickers of urothelial neoplasms is critical to avoid rendering false positive diagnoses of malignancy.
How to cite this article:
Dr. Prithal G, Dr. Smitha B, Dr. Muktha R Pai, Dr. Sandhya I and Dr. Purnima S Rao. Non-neoplastic urothelial lesions and mimickers of malignancy: Take Cognizance - Avoid negligence. International Journal of Clinical and Diagnostic Pathology. 2020; 3(1): 435-442. DOI: 10.33545/pathol.2020.v3.i1g.207
International Journal of Clinical and Diagnostic Pathology