Introduction: Intra-operative frozen section plays an important role in the management of surgical patients and yet it must be used prudently to avoid the indiscriminate usage of this important technique as it is subject to many limitations in comparison to the routine paraffin embedded tissue sections. In this study we have attempted to look at the concordance between the intraoperative frozen section diagnosis versus the regular histopathological diagnosis in our patients.
Aim of the study: To correlate the diagnosis given on Frozen section with Histopathological diagnosis.
Materials and Methods: This was a prospective study carried over a period of six months, from January 2019 to June 2019. Intraoperative Frozen sections were compared with routine regular paraffin embedded histopathology diagnosis in 51 patients. Detailed clinical history like age, gender, site, duration of lesions were noted.
Results: Various specimen types were received for Frozen sections during the time frame of this study, which included bone, soft tissue, genitourinary, skin, brain, and gastrointestinal tract tissue samples. Frozen section requests included asking for a diagnosis of a lesion (72.5%), margin status of a resected specimen containing malignancy (3.92%), lymph node status for the presence of metastatic tumor (23.5%). All the 51 cases (100%) of frozen section impressions were concordant with routine histopathological diagnosis.
Conclusion: The Intra-operative consultation using Frozen section is a very useful tool and guides the surgeon to intraoperatively modify the surgical approach. However, regular histopathological analysis is the gold standard for diagnosis.