International Journal of Clinical and Diagnostic Pathology

Background: Various types of pathologies from inflammation to carcinoma are known to affect breast tissue in females. Some lesions are common in young females while others are more common in elderly age group. Accurate diagnosis is essential to relieve anxiety of patients. In case of carcinoma, early and accurate diagnosis can save the patient from metastases, thus reducing mortality and morbidity. Aims and objectives: This study is aimed to analyse the histopathological spectrum of various breast lesions and to study the distribution of breast diseases in different age groups and gender in our institute. Materials and Methods: It is a prospective study performed in the Department of pathology at Government Medical College/Government General Hospital Anantapuramu over a period of four years from January 2015 to December 2018. During this period a total of 310 breast specimens were received in the Department of pathology. Histopathological examination of specimens was done to know the spectrum of breast lesions. Results: Out of 310cases, 290cases were female and 20 cases were male. 185 cases were benign breast neoplasms, 123 cases were malignant neoplasms and 02 cases were inflammatory lesions. Among the 185 cases of benign breast neoplasms, 141 cases were fibroadenoma which was the most common benign breast lesion. Out of 123 malignant breast lesions, 2 cases were Duct cell carcinoma in situ and 121 cases were invasive malignant breast lesions. Out of which 97 cases were Invasive ductal carcinoma –NOS subtype which was the most common lesion. Conclusion: 59.68% of breast lesions were benign breast lesions proving to be the majority in incidence. 39.68 % of lesions were malignant breast lesions and 0.64% were inflammatory lesions. Benign lesions were common in second to fourth decade and malignancy in fifth and sixth decades.