International Journal of Clinical and Diagnostic Pathology

Introduction: Cardiac tumors constitute only 0.2% of all tumors. Primary cardiac tumors are extremely rare with an incidence of 0.0017 to 0.19. Cardiac myxomas are the most common benign neoplasm of the heart. The prevalence is rare and incidence is 0.001% to 0.03%. Objective: To review our experiences with this rare entity and highlight the various aspects of myxoma presentation, histopathology and diagnosis in Western Maharastrian Population. Methodology: A total of 18 cases were accrued from the histopathology files of MH Cardiothoracic centre from 2009-2019 and studied. Results: A total 18 cases were included in the analysis. Mean age was 45 years, with equal male to female ratio (50%). Patients ranged from 01 months to 84 years old. Echocardiography was the diagnostic technique employed. The tumor was demonstrated by angiocardiography prior to surgery. Hemodynamically, left atrial myxomas revealed moderately severe pulmonary hypertension and right atrial myxomas, with right atrial hypertension. There were 12 myxomas in the left atrium, 3 in the right atrium, 1 in left ventricle, 1 in the Aortic valve and one case of papillary fibroelastoma in left atrium was reported. Eighteen patients underwent open-heart operation with removal of the myxoma. The size of myxoma varied from friable centimetric fragments to globular mass measuring 8.5cm in greatest dimension. The mean dimension of myxoma measured on echocardiography was 3.69 cm. 77.7% percent had left sided and 16.6% had right sided myxoma. Conclusion: Our results showed that the prevalence of cardiac myxoma in Western Maharashtra is comparable with national and global estimates however the female to male ratio was same, no gender predominance was noted. The mean age of presentation was 45 years, slightly lower than global pattern. Mean greatest dimension was 3.69cm. Prevalence of right atrial myxoma was slightly higher in our sample compare to other national and international published literature.