Vol. 1, Issue 1, Part A (2018)

Objective: One of the most frequent complications and main causes of morbidity and death in critically ill patients are bloodstream infections. Reducing mortality and improving clinical outcomes require the early start of an effective antibiotic therapy.
Material and Methods: The Department of Pathology at Narayana Medical College and Hospital, Nellore, Andhra Pradesh, India conducted this prospective cross-sectional study. The study was conducted from April 2017 to March 2018 following informed consent from the patients and institutional ethical committee approval, the trial was initiated.
Results: Patients in intensive care units are at heightened risk for complications and mortality due to bloodstream infections. The significant disparity in BSI incidence reports can be ascribed to the diverse institutions, patient demographics, comorbidities, and durations of hospitalization that present varying risks to individuals. Thirty-eight out of fifty blood culture samples yielded good results. Various factors, including the microorganisms responsible for the infection in the intensive care unit, pre-existing risk factors, the speed of medicine administration, and the efficacy of the intervention, may contribute to bloodstream infection.
Conclusion: Clinicians must possess knowledge of common resistance mechanisms, risk factors for bloodstream infections caused by resistant bacteria, and optimal strategies for antibiotic treatment, source control, and surveillance as part of their comprehensive care for critically ill patients.